Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 641-650 of 757

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  1. Stigmasterol (HB4095)

    Description:

    Phytosterol with anticancer and many other biological actions. Farnesoid X receptor antagonist.

    Purity:

    >95%

    Pack:
    5g
    Price:
    $242
    Qty:
  2. Pack:
    10mg
    Price:
    $235
    Qty:
    Pack:
    50mg
    Price:
    $887
    Qty:
  3. Streptochlorin (HB4096)

    Description:

    TNFα-induced NF-κB activation inhibitor.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $396
    Qty:
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    Description:

    Calcium sensing receptor (CaSR) agonist. Induces MSC osteogenic differentiation.

    Pack:
    1g
    Price:
    $103
    Qty:
  5. SU 5402 (HB3133)

    Description:

    Potent FGFR and VEGFR inhibitor. Attenuates integrin β4-induced neural stem cell differentiation.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $138
    Qty:
  6. Pack:
    100mg
    Price:
    $91
    Qty:
  7. Pack:
    100mg
    Price:
    $45
    Qty:
  8. Swinholide A (HB4100)

    Description:

    Actin filament inhibitor. Disrupts actin cytoskeleton.

    Purity:

    >97%

    Pack:
    50μg
    Price:
    $398
    Qty:
  9. T3 (HB7470)

    Description:

    Thyroid hormone. Frequently used in various stem cell protocols.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    Qty:
    Pack:
    100mg
    Price:
    $59
    Qty:
    Pack:
    250mg
    Price:
    $145
    Qty:
  10. TAK 715 (HB0599)

    Description:

    Potent, p-38 MAP kinase inhibitor. Wnt/β-catenin signaling inhibitor.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $209
    Qty:
    Pack:
    50mg
    Price:
    $825
    Qty:
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