Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 561-570 of 757

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  1. Description:

    Potent, selective, competitive H2 receptor antagonist

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $69
    Qty:
  2. Rapamycin (HB2779)

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    Description:

    mTOR inhibitor and potent immunosuppressant. Also used in inducible gene editing methods (e.g. CRISPR/Cas9) and promotes hPSC differentiation.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $140
    Free trial
    Qty:
    Pack:
    5mg
    Price:
    $237
    Qty:
  3. Description:

    Selective, irreversible MAO-B inhibitor

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $70
    Qty:
  4. Pack:
    10mg
    Price:
    $147
    Qty:
    Pack:
    50mg
    Price:
    $602
    Qty:
  5. Rebeccamycin (HB4052)

    Description:

    Weak topoisomerase I inhibitor. Shows no activity against protein kninases.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $465
    Qty:
  6. Description:

    Neurotrophic factor related to BDNF, NT-3 and NT-4

    Pack:
    5μg
    Price:
    $74
    Qty:
    Pack:
    20μg
    Price:
    $123
    Qty:
    Pack:
    100μg
    Price:
    $223
    Qty:
  7. Description:

    Potent neural factor

    Pack:
    5μg
    Price:
    $97
    Qty:
    Pack:
    20μg
    Price:
    $253
    Qty:
  8. Description:

    Neurotrophin which enhances differentiation and survival of dopaminergic neurons

    Pack:
    2μg
    Price:
    $94
    Qty:
    Pack:
    10μg
    Price:
    $233
    Qty:
    Pack:
    100μg
    Price:
    $754
    Qty:
    Pack:
    500μg
    Price:
    $3,752
    Qty:
    Pack:
    1mg
    Price:
    $6,254
    Qty:
  9. Description:

    Neurotrophin involved in neuron development, survival and differentiation

    Pack:
    2μg
    Price:
    $90
    Qty:
    Pack:
    10μg
    Price:
    $235
    Qty:
  10. Pack:
    250mg
    Price:
    $760
    Qty:
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