Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Perlapine (HB4889)

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    Description:

    Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $33
    Qty:
    Pack:
    10mg
    Price:
    $132
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    Pack:
    50mg
    Price:
    $545
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  2. Description:

    Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Water soluble.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $44
    Qty:
    Pack:
    10mg
    Price:
    $133
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    Pack:
    50mg
    Price:
    $558
    Qty:
  3. PETCM (HB1292)

    Description:

    Caspase-3 activator

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $202
    Qty:
    Pack:
    250mg
    Price:
    $817
    Qty:
  4. Pack:
    10mg
    Price:
    $223
    Qty:
    Pack:
    50mg
    Price:
    $749
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  5. Pack:
    10mg
    Price:
    $173
    Qty:
    Pack:
    50mg
    Price:
    $700
    Qty:
  6. Pack:
    10mg
    Price:
    $213
    Qty:
    Pack:
    50mg
    Price:
    $838
    Qty:
  7. Pack:
    300 tests
    Price:
    $215
    Qty:
    Pack:
    100μg
    Price:
    $223
    Qty:
  8. Description:

    5-HT3 receptor agonist

    Pack:
    100mg
    Price:
    $85
    Qty:
  9. Description:

    GSK-3β inhibitor

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $180
    Qty:
  10. Pack:
    10mg
    Price:
    $234
    Qty:
    Pack:
    50mg
    Price:
    $934
    Qty:
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