Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Pack:
    10mg
    Price:
    $235
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    Pack:
    50mg
    Price:
    $887
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  2. Streptochlorin (HB4096)

    Description:

    TNFα-induced NF-κB activation inhibitor.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $396
    Qty:
  3. Streptozocin (HB4097)

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    Description:

    Antibiotic. Diabetes inducer.

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $47
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    Pack:
    500mg
    Price:
    $151
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    Pack:
    1g
    Price:
    $213
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    Pack:
    5g
    Price:
    $936
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    Description:

    Calcium sensing receptor (CaSR) agonist. Induces MSC osteogenic differentiation.

    Pack:
    1g
    Price:
    $103
    Qty:
  5. SU 5402 (HB3133)

    Description:

    Potent FGFR and VEGFR inhibitor. Attenuates integrin β4-induced neural stem cell differentiation.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $138
    Qty:
  6. Pack:
    1mg
    Price:
    $45
    Qty:
    Pack:
    5mg
    Price:
    $116
    Qty:
  7. Pack:
    50mg
    Price:
    $58
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    Pack:
    100mg
    Price:
    $110
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  8. Pack:
    100mg
    Price:
    $91
    Qty:
  9. Pack:
    100mg
    Price:
    $45
    Qty:
  10. Description:

    5-HT1D, 5-HT1B and 5-HT1A receptor agonist

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $108
    Qty:
    Pack:
    50mg
    Price:
    $372
    Qty:
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