Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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Items 1201-1210 of 1413

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  1. Spironolactone (HB2799)

    Description:

    Mineralocorticoid and androgen receptor antagonist

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $54
    Qty:
  2. Splitomicin (HB4091)

    Description:

    Potent,selective, cell permeable yeast NAD+-dependent HDAC Sir2p inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $359
    Qty:
  3. Pack:
    10mg
    Price:
    $246
    Qty:
    Pack:
    50mg
    Price:
    $968
    Qty:
  4. Pack:
    10mg
    Price:
    $102
    Free trial
    Qty:
    Pack:
    50mg
    Price:
    $393
    Qty:
    Pack:
    10mM (add 1ml water)
    Price:
    $66
    Qty:
  5. Stattic (HB1437)

    Description:

    Selective STAT3 inhibitor

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $63
    Qty:
    Pack:
    25mg
    Price:
    $254
    Qty:
  6. Stauprimide (HB3011)

    Description:

    NME2 nuclear translocation inhibitor. Primes ESCs for differentiation.

    Purity:

    >98%

    Pack:
    100μg
    Price:
    $188
    Qty:
  7. Pack:
    1mg
    Price:
    $408
    Qty:
  8. Description:

    Glycoside with various biological actions

    Purity:

    >95%

    Pack:
    50mg
    Price:
    $348
    Qty:
  9. Stigmasterol (HB4095)

    Description:

    Phytosterol with anticancer and many other biological actions. Farnesoid X receptor antagonist.

    Purity:

    >95%

    Pack:
    5g
    Price:
    $242
    Qty:
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