Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 41-50 of 77

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  1. MS-275 (HB3983)

    Description:

    HDAC 1 inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $310
    Qty:
  2. Neuropathiazol (HB3105)

    Description:

    Selective neuronal differentiation inducer in hippocampal neural progenitors

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $187
    Qty:
    Pack:
    50mg
    Price:
    $733
    Qty:
  3. Description:

    LPA1 and LPA2 agonist. Inhibits differentiation of neural stem cells (NSCs) into neurons.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $70
    Qty:
    Pack:
    5mg
    Price:
    $213
    Qty:
  4. Pack:
    100mg
    Price:
    $86
    Qty:
  5. Pack:
    50mg
    Price:
    $529
    Qty:
  6. PD 173074 (HB3584)

    Description:

    FGFR1/ FGFR3 inhibitor. Inhibits oligodendrocyte progenitor proliferation and differentiation.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $215
    Qty:
    Pack:
    50mg
    Price:
    $835
    Qty:
  7. PluriSln 1 (HB3573)

    Description:

    SCD1 inhibitor. Selectively eliminates undifferentiated hPSCs from culture.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $431
    Qty:
  8. PNU 74654 (HB0528)

    Description:

    β-catenin inhibitor. Wnt pathway inhibitor. Promotes neural differentiation of hPSCs.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $574
    Qty:
  9. Purmorphamine (HB3412)

    Description:

    Smo receptor agonist that activates the hedgehog pathway. Induces mesenchymal and iPSC differentiation.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $171
    Qty:
    Pack:
    25mg
    Price:
    $386
    Qty:
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