Target

Selective TGF-β signaling inhibitor. Induces cardiomyocyte differentiation in ESCs.

α7 nicotinic acetylcholine receptor positive allosteric modulator. Activates GluCI/GlyCI chemogenetic channels. Shows antiviral activity.

Potent PORCN inhibitor

Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.

Potent PORCN inhibitor. Supresses R1 ESCs self renewal.

Cell permeable, non-fluorescent F-actin probe. Induces actin polymerization and stabilization.

Piezo1 channel activator

Novel, inactive photocaged derivative of raseglurant which can be uncaged with violet light. Shows light-dependent analgesic activity in vivo.

Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Freebase.

Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.