Target

Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

Potent, selective TRPA1 channel blocker

Selective cPLA₂ inhibitor

Potent dopamine D₄ receptor partial agonist

GABA receptor agonist and glutamatergic modulator

Fluorogenic tri-peptide substrate. Useful for measuring trypsin-like 20S proteasome peptidase activity.

Competitive NMDA receptor partial agonist

Potent, selective GluK1 (GluR5) kainate receptor antagonist

Sildenafil analog

Serotonin N-acetyltransferase substrate