Target

Inhibits α-MSH release inhibitors. Also increase dopamine levels.

Selective H₁ receptor inverse agonist

5-HT₁/5-HT₂ antagonist. Shows affinity for 5-HT₆ and 5-HT₇.

L-aromatic amino acid decarboxylase inhibitor

Non-selective 5-HT₂ receptor antagonist. Shows activity at other receptors.

Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.

5-HT and norepinephrine re-uptake inhibitor (SNRI)

Selective leukotriene LTD4 receptor antagonist. Potent MRP1 inhibitor.

Selective mGlu₃ negative allosteric modulator

Caged glutamate that rapidly and efficiently releases glutamate when photolysed