Hedgehog signaling

Topoisomerase II inhibitor

IκB kinase inhibitor. NF-κB inhibitor.

Potent, selective HDAC inhibitor

Selective PPARγ agonist

Potent L- / N-type calcium channel blocker

Selective mGlu₄ agonist

GluN2C / GluN2D subunit selective NMDA receptor positive allosteric modulator

Broad spectrum anticancer agent. Apoptosis inducer.

Potent, selective 5-HT uptake inhibitor

Potent, selective and irreversible proteasome inhibitor