Hedgehog signaling

LPA1 and LPA2 agonist. Inhibits differentiation of neural stem cells (NSCs) into neurons.

PLA₂ inhibitor

Inhibitor of mitochondrial function

Farnesyltransferase (FTase) inhibitor

Potent, selective P-type / Q-type Ca²⁺ channel blocker

Potent, selective P-type / Q-type Ca²⁺ channel blocker

Small molecule RNA polymerase II inhibitor

Potent, selective 5-HT₃ antagonist

Irreversible calmodulin antagonist

Group III mGlu agonist. Increases stem cell neurogenesis.