Product overview

Name Neuropeptide S (mouse)
Biological description

Neuropeptide S (NPS) is an endogenous neuropeptide which acts at the Neuropeptide S receptor (NPSR). It is expressed by a limited number of neurons in the brainstem.

It promotes arousal and anxiolytic-like effects and is thought to be involved in in mood control and vigilance.

Purity >95%
Description Neuropeptide S receptor (NPSR) agonist
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Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in water (2 mg/ml)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
Chemical name Neuropeptide S (mouse)
Molecular Weight 2182.47
Chemical structure Neuropeptide S (mouse)| [412938-74-0] Chemical Structure
Molecular Formula C93H156N34O27
Sequence (one letter) SFRNGVGSGAKKTSFRRAKQ
CAS Number 412938-74-0
PubChem identifier 54581309
SMILES [H]N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(O)=O
InChiKey XBNIXBCJICZFRR-GYDKITGDSA-N

References for Neuropeptide S (mouse)

References are publications that support the biological activity of the product
  • Exploring the role of neuropeptide S in the regulation of arousal: a functional anatomical study

    Adori C et al (2016) Brain Struct Funct 221(7) : 3521-46
  • Neuropeptide S- and Neuropeptide S receptor-expressing neuron populations in the human pons

    Adori C et al (2015) Front Neuroanat 9 : 126

2 Item(s)