Product overview

Name Neuropeptide S (mouse)
Biological description

Neuropeptide S (NPS) is an endogenous neuropeptide which acts at the Neuropeptide S receptor (NPSR). It is expressed by a limited number of neurons in the brainstem.

It promotes arousal and anxiolytic-like effects and is thought to be involved in in mood control and vigilance.

Purity >95%
Description Neuropeptide S receptor (NPSR) agonist
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Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in water (2 mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

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Dilution

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Chemical Data

Purity >95%
Chemical name Neuropeptide S (mouse)
Molecular Weight 2182.47
Chemical structure Neuropeptide S (mouse)| [412938-74-0] Chemical Structure
Molecular Formula C93H156N34O27
Sequence (one letter) SFRNGVGSGAKKTSFRRAKQ
CAS Number 412938-74-0
PubChem identifier 54581309
SMILES [H]N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(O)=O
InChiKey XBNIXBCJICZFRR-GYDKITGDSA-N

References for Neuropeptide S (mouse)

References are publications that support the biological activity of the product
  • Exploring the role of neuropeptide S in the regulation of arousal: a functional anatomical study

    Adori C et al (2016) Brain Struct Funct 221(7) : 3521-46
  • Neuropeptide S- and Neuropeptide S receptor-expressing neuron populations in the human pons

    Adori C et al (2015) Front Neuroanat 9 : 126

2 Item(s)