Stem cells
Stem cells are unspecialized cells that are capable of self-renewal through mitotic cell division. They may be induced to form more specialized cells by a process termed cellular differentiation.The main types of stems cells are embryonic stem cells (ESCs) found in blastocysts; adult (or somatic) stem cells, found in adult tissues, induced pluripotent stem cells (iPSCs) and cancer stem cells (CSCs). Small molecule pharmacological tools can be used to manipulate signalling pathways during the in vitro culture of stem cells. These tools can be used to target signaling pathways that control cell proliferation and differentiation. Researchers can save up to 50% on stem cell research tools from Hello Bio - they are around half the price of other suppliers.
View products: Differentiation | Organoids | Proliferation/Self-renewal | Reprogramming | Stem Cell Signaling View resources: Stem Cell Research Tools & Mini-Reviews
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Gatifloxacin (HB3263)
Description:Antibiotic; bacterial type II topoisomerase inhibitor. Activates ESC short term renewal.
Purity:>98%
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Go 6983 (HB0303)
Description:Broad spectrum PKC inhibitor. Optimizes naïve human pluripotent stem cell growth and viability
Purity:>98%
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H 89 dihydrochloride (HB0314)
Description:Potent, non-selective kinase inhibitor.Also improves dissociate hESCs survival and clonogenicity.
Purity:>99%
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IQ 1 (HB3282)
Description:Wnt pathway activator. Maintains ESC pluripotency in Wnt3a treated cells.
Purity:>99%
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IWP 2 (HB0344)
Description:Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.
Purity:>98%
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JF-NP-26 (Caged-Raseglurant) (HB6127)
Description:Novel, inactive photocaged derivative of raseglurant which can be uncaged with violet light. Shows light-dependent analgesic activity in vivo.
Purity:>98%
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