TLR7

TLR1/TLR2 agonist and potent NF-κB activator. Induces cytokine production.

FGFR1/ FGFR3 inhibitor. Inhibits oligodendrocyte progenitor proliferation and differentiation.

Broad spectrum PKC agonist

Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator

Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Water soluble.

Caspase-3 activator

5-HT₃ receptor agonist

PKC activator. Widely used for THP-1 cell differentiation and with ionomycin for stimulating cytokine production

p53 inhibitor and Aryl hydrocarbon receptor agonist. Supresses ESC self renewal.

Selective PPARγ agonist