JAK/STAT
JAK/STAT signaling plays a critical role in the immune response. It is plays a major role in transferring signals from cell-membrane receptors to the nuclear. The JAK/STAT signaling pathway is essential for a wide range of cytokines and growth factors which lead to critical immunological cellular events.
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Pluripotin (HB2223)
Description:Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal.
Purity:>98%
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Pexidartinib (PLX3397) (HB8991)
Description:Potent CSF-1R inhibitor. Widely used microglia-depletion agent.
Purity:>98%
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PLX4720 (HB4030)
Description:Potent and selective cell permeable B-Raf and C-Raf inhibitor
Purity:>99%
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PLX5622 (HB17582)
Description:Highly selective, potent CSF-1R inhibitor. Widely used microglia-depletion agent.
Purity:>98%
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PNU 37883 hydrochloride (HB1105)
Description:Selective vascular KATP channel antagonist
Purity:>99%
