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JAK/STAT signaling plays a critical role in the immune response. It is plays a major role in transferring signals from cell-membrane receptors to the nuclear. The JAK/STAT signaling pathway is essential for a wide range of cytokines and growth factors which lead to critical immunological cellular events.
Ro 25-6981 maleate (HB0554)
Description:Selective negative allosteric modulator of GluN2B (NR2B) containing NMDARs
Purity:>98%
Ro 32-0432 hydrochloride (HB4820)
Description:Potent, selective PKC inhibitor. GRK inhibitor.
Purity:>98%
Ro 61-8048 (HB0556)
Description:Potent, competitive kynurenine 3-hydroxylase inhibitor
Purity:>99%
(R)-(-)-Rolipram (HB2898)
Description:Potent, selective PDE4 inhibitor. Enantiomer of Rolipram.
Purity:>98%