Microtubule

G(2)/M phase cell cycle inhibitor

Potent adenosine deaminase and PDE2 inhibitor. Supresses spontaneous hESC differentiation. Also maintains pluripotency of hESCs in the absence of exogenous cytokines.

Leukocyte elastase inhibitor

Non-competitive, GluN2B subunit selective NMDA receptor antagonist

Potent CK2 inhibitor

Protein synthesis inhibitor

Potent, selective sodium glucose co-transporter 2 (SGLT-2) inhibitor

Derivative of aszonalenin, a substance P inhibitor.

Selective mineralcorticoid receptor antagonist

Potent, selective and irreversible 20S proteasome inhibitor