Cytokine Storm / Immune response signaling
Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.
View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling
(R)-3-Hydroxybutyric acid (HB4640)
Description:Endogenous HDAC1, HDAC3 and HDAC4 inhibitor
Purity:>98%
(S)-3-Hydroxybutyric acid (HB4641)
Description:Endogenous HDAC1, HDAC3 and HDAC4 inhibitor
Purity:>98%
- Description:
Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).
Purity:>98%
- Description:
Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).
Purity:>98%
(R,R)-Hymeglusin (HB3701)
Description:Specific and irreversible HMG-CoA synthase inhibitor
Purity:>95%
10Z-Hymenialdisine (HB1264)
Description:Pan kinase inhibitor. Potently inhibits MEK1, Cdk1, Cdk2, Cdk3 and Cdk5 and GSK-3β.
Purity:>97%
I-BET 151 hydrochloride (HB1446)
Description:BET bromodomain inhibitor, also promotes differentiation of hiPSCs into megakaryocytes
Purity:>98%