CRISPR/ Gene editing
Small molecules such as 4-Hydroxytamoxifen ≥70% Z isomer can enhance the overall efficiency and targeting precision of CRISPR/Cas-9-mediated genome editing. Researchers can save up to 50% on small molecules for CRISPR / Cas9 genome editing - they are up to half the price of other suppliers.
View resources: Small Molecules for Genome Editing | Inducible CreER and CRISPR/Cas9 genome engineering techniques using small molecules
- Description:
Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).
Purity:>98%
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ICI 182,780 (Fulvestrant) (HB2501)
Description:Estrogen receptor (ER) antagonist and high affinity GPER agonist
Purity:>99%
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Mifepristone (HB2783)
Description:Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.
Purity:>99%
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Muristerone A (HB3985)
Description:Ecdysone receptor (EcR) agonist. Apoptosis inducer.
Purity:>95%
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Pifithrin-α hydrobromide (HB2478)
Description:p53 inhibitor and Aryl hydrocarbon receptor agonist. Supresses ESC self renewal.
Purity:>98%
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Pioglitazone hydrochloride (HB2554)
Description:Selective PPARγ agonist. Enhances mESCs proliferation and survival.
Purity:>99%
