Product overview

Name Muristerone A
Purity >95%
Description Ecdysone receptor (EcR) agonist. Apoptosis inducer.
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Biological Data

Biological description Potent member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. Analog of ecdysone with similar properties to ponasterone A. Inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Induces apoptosis in cells transfected with wild-type Bax. Induces expression of beta-galactosidase. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells. Insect steroid hormone involved in regulating metamorphosis, causing a response to G2 cell cycle arrest. Major molting hormone in some insects. Has protective effects in plants.

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >95%
Molecular Weight 496.6
Chemical structure Muristerone A [38778-30-2] Chemical Structure
Molecular Formula C27H44O8
CAS Number 38778-30-2
PubChem identifier 122217
SMILES O[C@@H]1[C@H](O)C[C@](C(C=C3[C@@]([H])2[C@H](O)C[C@@]4(C)[C@](O)3CC[C@@]([H])4[C@](O)(C)[C@H](O)CCC(C)C)=O)(O)[C@]2(C)C1
InChiKey LRJUYAVTHIEHAI-LDJCFVSYSA-N
Appearance White to off-white solid