DREADDs
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
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CGP 54626 hydrochloride (HB0959)
Description:Potent, selective GABAB receptor antagonist
Purity:>98%
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CGP 55845 hydrochloride (HB0960)
Description:Potent, selective GABAB receptor antagonist
Purity:>98%
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CGS 21680 hydrochloride (HB2097)
Description:Prototypic, selective A2A receptor agonist
Purity:>98%
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p-Chlorophenylalanine (HB1647)
Description:Irreversible tryptophan hydroxylase inhibitor. Depletes 5-HT.
Purity:>99%
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(R,S)-CHPG sodium salt (HB0034)
Description:Selective mGluR5 agonist. Water soluble sodium salt.
Purity:>99%
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(±)-Clopidogrel hydrochloride (HB1974)
Description:Selective, irreversible P2Y12 receptor antagonist
Purity:>99%
