DREADDs

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 1-10 of 240

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  1. Pack:
    50mg
    Price:
    $55
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    Pack:
    250mg
    Price:
    $104
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    Pack:
    1g
    Price:
    $349
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  2. A 83-01 (HB3218)

    1  Review
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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $80
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    Pack:
    25mg
    Price:
    $270
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  3. Description:

    Potent dopamine D4 receptor partial agonist

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $568
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  4. Pack:
    10mg
    Price:
    $243
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    Pack:
    50mg
    Price:
    $917
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  5. AM251 (HB2776)

    3  Reviews
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    Description:

    Potent, selective CB1 receptor antagonist / inverse agonist

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $56
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    Pack:
    10mg
    Price:
    $124
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    Pack:
    50mg
    Price:
    $476
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  6. Pack:
    10mg
    Price:
    $152
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    Pack:
    50mg
    Price:
    $626
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  7. L-AP4 (HB0370)

    3  Reviews
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    Description:

    L-AP4 is a selective group III mGluR agonist which inhibits synaptic transmission.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $74
    Qty:
    Pack:
    10mg
    Price:
    $143
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    Pack:
    25mg
    Price:
    $298
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    Pack:
    50mg
    Price:
    $592
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