Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.
2,4-Diamino-6-hydroxypyrimidine (HB0070)
Description:GTP cyclohydrolase I (GCH1) inhibitor
Purity:>98%
5,7-Dichlorokynurenic acid (HB0078)
Description:Potent, selective, competitive glycine site NMDA receptor antagonist
Purity:>98%
Dihydrochlamydocin (HB3874)
Description:Phytotoxin. Derivative of the HDAC inhibitor chlamydocin.
Purity:>95%
Dihydroergocristine mesylate (HB1611)
Description:5-HT antagonist. Also partial agonist at adrenergic and dopaminergic receptors.
Purity:>98%
Dihydroergotamine mesylate (HB1612)
Description:Partial α-adrenergic agonist, partial D2 agonist and 5-HT antagonist
Purity:>98%