Nuclear Receptors

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Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.

Items 471-480 of 1076

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  1. Description:

    Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $47
    Qty:
    Pack:
    50mg
    Price:
    $183
    Qty:
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    Description:

    Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $69
    Qty:
    Pack:
    50mg
    Price:
    $239
    Qty:
  3. Description:

    Antibacterial and antifungal compound

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $196
    Qty:
  4. Description:

    Specific and irreversible HMG-CoA synthase inhibitor

    Purity:

    >95%

    Pack:
    500μg
    Price:
    $210
    Qty:
    Pack:
    1mg
    Price:
    $372
    Qty:
  5. Description:

    Pan kinase inhibitor. Potently inhibits MEK1, Cdk1, Cdk2, Cdk3 and Cdk5 and GSK-3β.

    Purity:

    >97%

    Pack:
    250μg
    Price:
    $201
    Qty:
    Pack:
    1mg
    Price:
    $669
    Qty:
  6. Description:

    Selective TRPC6 channel activator and neurotransmitter re-uptake inhibitor

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $261
    Qty:
  7. Hypotaurine (HB2656)

    Description:

    Non-selective endogenous glycine receptor agonist 

    Purity:

    >95%

    Pack:
    100mg
    Price:
    $101
    Qty:
  8. Pack:
    100μg
    Price:
    $243
    Qty:
  9. Description:

    BET bromodomain inhibitor, also promotes differentiation of hiPSCs into megakaryocytes

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $1,242
    Qty:
  10. IBMX (HB3000)

    Description:

    Non-selective, competitive cAMP and cGMP PDE inhibitor. Facilitates neural progenitor cell differentiation.

    Purity:

    >98%

    Pack:
    100mg
    Price:
    Qty:
    Pack:
    500mg
    Price:
    $134
    Qty:
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