Estrogen and related

Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Water soluble.

Selective D₃ receptor agonist

α₁ and α₂ adrenoceptor antagonist

D₂ receptor antagonist. Also 5-HT₃ and nAChR antagonist.

5-HT₂ and D₂ antagonist. Atypical antipsychotic.

AMPA receptor agonist and group I mGlu agonist

Potent, selective, competitive H₂ receptor antagonist

mGlu₅ negative allosteric modulator

Na⁺ channel blocker / glutamate inhibitor. TREK-1 K2P channel activator. Water soluble.

5-HT_2A and D₂ receptor antagonist