Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
AMD 3100 octahydrochloride (HB2739)
Description:Potent, selective CXCR4 antagonist. Mobilizes hematopoietic stem cells.
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- Description:
Ribosome-borne protein folding activity (RPFA) inhibitor
Purity:>99%
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6-Aminophenanthridine (HB3730)
Description:Ribosome-borne protein folding activity (RPFA) inhibitor
Purity:>97%
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4-Aminopyridine (4-AP) (HB1073)
Description:Non-selective voltage gated K+ channel blocker
Purity:>99%
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Amisulpride (HB1879)
Description:Potent, selective dopamine D2 and D3 receptor antagonist. Atypical antipsychotic.
Purity:>98%
