AMG 9810

Name: AMG 9810
Brand: Hello Bio
SKU: HB1188
Price: 158 USD
Availability: InStock

(HB1188)

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Technical documents: SDS CoA Datasheet

Product overview

Name

AMG 9810

Purity

>98%

Description

Potent, selective, competitive TRPV1 channel antagonist

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) References (3) Frequently bought together

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Biological Data

Biological description

Potent, selective and competitive TRPV1 channel antagonist (IC₅₀ values are 24.5 and 85.6 nM for human and rat TRPV1 respectively). Competitively inhibits capsaicin binding to rat TRPV1. Displays antihyperalgesic effects.

Solubility & Handling

Storage instructions

+4°C (desiccate)

Solubility overview

Soluble in DMSO (50mM) or ethanol (100mM)

Important

This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

More Info

Dilution

More Info

Chemical Data

Purity

>98%

Chemical name

(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propenamide

Molecular Weight

337.42

Chemical structure

Molecular Formula

C₂₁H₂₃NO₃

CAS Number

545395-94-6

PubChem identifier

680502

SMILES

CC(C)(C)C1=CC=C(C=C1)\C=C\C(=O)NC1=CC=C2OCCOC2=C1

InChiKey

GZTFUVZVLYUPRG-IZZDOVSWSA-N

Technical guides

Understanding purity and quality - a guide for life scientists (159.4 KB)

References for AMG 9810

References are publications that support the biological activity of the product

Increased acid responsiveness in vagal sensory neurons in a guinea pig model of eosinophilic esophagitis.
Hu Y et al (2014) Am J Physiol Gastrointest Liver Physiol 307(2) : G149-57.
Read more (PubMedID: 24875100)
No requirement of TRPV1 in long-term potentiation or long-term depression in the anterior cingulate cortex.
Liu MG et al (2014) Mol Brain 7 : 27
Read more (PubMedID: 24708859)
AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties.
Gavva NR et al (2005) J Pharmacol Exp Ther 313(1) : 474-84.
Read more (PubMedID: 15615864)

Potent, selective, competitive TRPV1 channel antagonist

Order: HB1188
Pack	Price	Qty
10mg	$158
50mg	$629

AMG 9810

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for AMG 9810

Increased acid responsiveness in vagal sensory neurons in a guinea pig model of eosinophilic esophagitis.

No requirement of TRPV1 in long-term potentiation or long-term depression in the anterior cingulate cortex.

AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties.

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AMG 9810

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for AMG 9810

Increased acid responsiveness in vagal sensory neurons in a guinea pig model of eosinophilic esophagitis.

No requirement of TRPV1 in long-term potentiation or long-term depression in the anterior cingulate cortex.

AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties.

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About you

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New Products in this Area