Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
SAG (HB3107)
Description:Cell permeable Sonic hedgehog (Shh) agonist and Smo agonist. Enhances neuronal differentiation of iPSC into dopaminergic neurons.
Purity:>98%
SAG Analog (highly active) (HB4070)
Description:Highly active Sonic hedgehog agonist. Also smoothened (Smo) agonist.
Purity:>98%
SAG Analog (LowTox) (HB4071)
Description:Low toxicity Sonic hedgehog agonist. Also smoothened (Smo) agonist.
Purity:>98%