Product overview

Name Rufinamide
Alternative names CGP 33101
Purity >99%
Description Na+ channel blocker
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Rufinamide product vial image | Hello Bio

Biological Data

Biological description Na+ channel blocker. Shows higher selectivity for Nav1.7. Also mGluR5 antagonist. A novel triazole derivative. Prolongs sodium channel inactivation. Displays anticonvulsant and antiepileptic actions.

Solubility & Handling

Solubility overview Soluble in DMSO (100mM)
Storage instructions room temperature (desiccate)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >99%
Chemical name 1-[(2,6-Difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide
Molecular Weight 238.19
Chemical structure Rufinamide  [106308-44-5] Chemical Structure
Molecular Formula C10H8F2N4O
CAS Number 106308-44-5
PubChem identifier 129228
SMILES O=C(N)C1=CN(CC2=C(F)C=CC=C2F)N=N1
InChiKey POGQSBRIGCQNEG-UHFFFAOYSA-N

References for Rufinamide

References are publications that support the biological activity of the product

3 Item(s)

Publications
These publications cite the use of Rufinamide purchased from Hello Bio:
  • Modulating voltage-gated sodium channels to enhance differentiation and sensitize glioblastoma cells to chemotherapy.

    Giammello F et al (2024) Cell communication and signaling : CCS 22 : 434
    PubMedID: 39251990

1 Item