Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
- Description:
Fluorescent β2 adrenoceptor antagonist
- Description:
Fluorescent 5-HT1A receptor antagonist
Caffeine (HB2846)
Description:Non-selective, competitive adenosine receptor antagonist / PDE inhibitor
Calphostin C (HB0160)
Description:Potent, selective PKC inhibitor. Also antagonizes the Tcf/β-catenin complex
Purity:>95%
Calyculin A (HB0161)
Description:Potent, selective protein phosphatase 1 / 2A inhibitor
Purity:>98%