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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
Eliprodil (HB0274)
Description:Non-competitive, GluN2B subunit selective NMDA receptor antagonist
Purity:>98%
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Empagliflozin (HB4638)
Description:Potent, selective sodium glucose co-transporter 2 (SGLT-2) inhibitor
Purity:>98%
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epi-Aszonalenin A (HB3889)
Description:Derivative of aszonalenin, a substance P inhibitor.
Purity:>95%
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Epoxomicin (HB3890)
Description:Potent, selective and irreversible 20S proteasome inhibitor
Purity:>97%
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