DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
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2,5-Dimethyl-celecoxib (HB3717)
Description:Shows no COX-2 inhibitory function. Analog of celecoxib.
Purity:>99%
- Description:
Potent antiviral compound
Purity:>97%
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Disulfiram (HB1119)
Description:Reversibly stimulates SERCA Ca2+-ATPase. V-ATPase inhibitor.
Purity:>97%
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DMNQ (HB3876)
Description:Cell-permeable, redox cycling quinone. Induces ROS generation.
Purity:>99%
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DMSO (Sterile-filtered) (HB3262)
Description:Widely used solvent. Improves direct differentiation of pluripotent stem cells and used as a stem cell cryoprotectant
Purity:>99.9%
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