Product overview

Name DMNQ
Purity >99%
Description Cell-permeable, redox cycling quinone. Induces ROS generation.
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Biological Data

Biological description Cell permeable, non-alkylating, non-thiol, adduct-forming, redox cycling quinone. Intracellular superoxide anion formation/ROS generation inducer. Anticancer agent. Shown to induce cell proliferation, apoptosis, necrosis and necroptosis in vitro, dependent on concentration, time, temperature and cell type. Valuable tool for the generation of reactive oxygen species (ROS) in order to study the role of ROS in cell toxicity, apoptosis and necrosis. Useful as reference compound in characterizing the effects of oxidative stress. Can be used to eliminate any mechanistic ambiguity involving redox cycling quinoids as the source of reactive oxidant species/oxidative stress in biological studies.

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >99%
Chemical name 2,3-Dimethoxy-1,4-naphthoquinone
Molecular Weight 218.2
Chemical structure DMNQ [6956-96-3] Chemical Structure
CAS Number 6956-96-3
SMILES COC1=C(OC)C(=O)c2ccccc2C1=O
InChiKey ZEGDFCCYTFPECB-UHFFFAOYSA-N
Appearance Yellow crystalline solid