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Dimaprit dihydrochloride

(HB2626)
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Product overview

Name Dimaprit dihydrochloride
Purity >95%
Description Selective H2 receptor agonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (4)
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Biological Data

Biological description Selective H2 receptor agonist. Also inhibits nNOS (IC50 = 49 µM for rat nNOS). Shows cytoprotective and hypotensive actions.

Solubility & Handling

Solubility overview Soluble in water (100 mM)
Storage instructions Room temperature (desiccate)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
Chemical name S-(3-Dimethylaminopropyl)isothioure a dihydrochloride
Molecular Weight 234.19
Chemical structure Dimaprit dihydrochloride [23256-33-9] Chemical Structure
Molecular Formula C6H15N3S.2HCl
CAS Number 23256-33-9
PubChem identifier 90045
SMILES CN(C)CCCSC(=N)N.Cl.Cl
InChi InChI=1S/C6H15N3S.2ClH/c1-9(2)4-3-5-10-6(7)8;;/h3-5H2,1-2H3,(H3,7,8);2*1H
InChiKey DFWCPLGXFMSUCW-UHFFFAOYSA-N
MDL number MFCD00069260

References for Dimaprit dihydrochloride

References are publications that support the biological activity of the product

  • Suppression of ischaemia-induced cytokine release by dimaprit and amelioration of liver injury in rats.

    Motoki A et al (2008) Basic Clin Pharmacol Toxicol 102(4) : 394-8.
    Read more (PubMedID: 18312491)

  • Nitric oxide synthase inhibition by dimaprit and dimaprit analogues.

    Paquay JB et al (1999) Br J Pharmacol 127(2) : 331-4.
    Read more (PubMedID: 10385230)

  • Cardiovascular effects of the novel histamine H2 receptor agonist amthamine: interaction with the adrenergic system.

    Coruzzi G et al (1996) Naunyn Schmiedebergs Arch Pharmacol 353(4) : 417-22.
    Read more (PubMedID: 8935708)

  • Dimaprit -(S-[3-(N,N-dimethylamino)prophyl]isothiourea) - a highly specific histamine H2 -receptor agonist. Part 1. Pharmacology.

    Parsons ME et al (1977) Agents Actions 7(1) : 31-7.
    Read more (PubMedID: 871093)

4 Item(s)

Grouped product items
Order: HB2626
Pack PriceQty
10mg
$98
100mg
$117
250mg
$276
Selective H2 receptor agonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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