G protein coupled receptors

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G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.

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Items 21-30 of 59

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  1. FK 506 (HB0289)

    Description:

    Potent calcineurin phosphatase 2B inhibitor. Enhances osteoblastic differentiation in mesenchymal cells.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $118
    Qty:
    Pack:
    50mg
    Price:
    $494
    Qty:
  2. Pack:
    10mg
    Price:
    $75
    Qty:
    Pack:
    50mg
    Price:
    $305
    Qty:
  3. Forskolin (HB1348)

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    Description:

    Cell permeable, reversible adenylyl cyclase activator. Neuronal differentiation inducer. Used in production of liver organoids.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $124
    Free trial
    Qty:
    Pack:
    50mg
    Price:
    $523
    Qty:
  4. Description:

    BET bromodomain inhibitor, also promotes differentiation of hiPSCs into megakaryocytes

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $1,242
    Qty:
  5. IBMX (HB3000)

    Description:

    Non-selective, competitive cAMP and cGMP PDE inhibitor. Facilitates neural progenitor cell differentiation.

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $48
    Qty:
    Pack:
    500mg
    Price:
    $134
    Qty:
  6. ISX 9 (HB3401)

    Description:

    Neurogenic agent. Induces SVZ progenitor neuronal differentiation and cardiomyogenic differentiation.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $185
    Qty:
  7. ITD 1 (HB3446)

    Description:

    Selective TGF-β signaling inhibitor. Induces cardiomyocyte differentiation in ESCs.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $213
    Qty:
    Pack:
    50mg
    Price:
    $824
    Qty:
  8. IWP 4 (HB3066)

    Description:

    Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $534
    Qty:
  9. Pack:
    10mg
    Price:
    $188
    Qty:
    Pack:
    25mg
    Price:
    $383
    Qty:
  10. KY 02111 (HB3465)

    Description:

    Wnt signaling inhibitor. Promotes differentiation of hESCs and iPSCs into cardiomyocytes.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $163
    Qty:
    Pack:
    50mg
    Price:
    $595
    Qty:
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