Ion channels
Ion channels are specialised pore-forming membrane proteins that allow ions to pass through the channel pore. They are classifed by their gating mechanism (eg. voltage-gated, ligand-gated, cyclic-nucleotide-gated & mechanosensitive) or ion selectivity (eg. calcium, potassium, sodium, chloride, proton). Researchers can save up to 50% on selective ion channel activators and blockers from Hello Bio - they are up to half the price of other suppliers.
View products: Voltage-Gated Ion Channels | Ligand-Gated Ion Channels (Ionotropic Receptors) | Ionophores | PiezoView Resources: Ion Channel Modulators
FK 506 (HB0289)
Description:Potent calcineurin phosphatase 2B inhibitor. Enhances osteoblastic differentiation in mesenchymal cells.
Purity:>99%
Fluoxetine hydrochloride (HB1600)
Description:Selective 5-HT uptake inhibitor. Affects differentiation of NSCs.
Purity:>98%
Forskolin (HB1348)
Description:Cell permeable, reversible adenylyl cyclase activator. Neuronal differentiation inducer. Used in production of liver organoids.
Purity:>98%
I-BET 151 hydrochloride (HB1446)
Description:BET bromodomain inhibitor, also promotes differentiation of hiPSCs into megakaryocytes
Purity:>98%
IBMX (HB3000)
Description:Non-selective, competitive cAMP and cGMP PDE inhibitor. Facilitates neural progenitor cell differentiation.
Purity:>98%
ISX 9 (HB3401)
Description:Neurogenic agent. Induces SVZ progenitor neuronal differentiation and cardiomyogenic differentiation.
Purity:>99%
ITD 1 (HB3446)
Description:Selective TGF-β signaling inhibitor. Induces cardiomyocyte differentiation in ESCs.
Purity:>98%
IWP 4 (HB3066)
Description:Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.
Purity:>98%
KY 02111 (HB3465)
Description:Wnt signaling inhibitor. Promotes differentiation of hESCs and iPSCs into cardiomyocytes.
Purity:>99%