Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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Items 141-150 of 719

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  1. Chetomin (HB1459)

    Description:

    HIF-1 formation inhibitor

    Purity:

    >90%

    Pack:
    1mg
    Price:
    $232
    Qty:
    Pack:
    5mg
    Price:
    $811
    Qty:
  2. CHIR 99021 (HB1261)

    Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $50
    Qty:
    Pack:
    2mg
    Price:
    Qty:
    Pack:
    5×2mg
    Price:
    $188
    Qty:
    Pack:
    10mg
    Price:
    $182
    Qty:
    Pack:
    5mg
    Price:
    $117
    Qty:
    Pack:
    25mg
    Price:
    $445
    Qty:
    Pack:
    50mg
    Price:
    $758
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $126
    Qty:
  3. Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons. Water soluble.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $229
    Qty:
    Pack:
    50mg
    Price:
    $916
    Qty:
  4. Description:

    Antiprion compound. Protein aggregation inhibitor.

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $313
    Qty:
  5. Pack:
    5mg
    Price:
    $67
    Qty:
    Pack:
    10mg
    Price:
    $94
    Qty:
    Pack:
    25mg
    Price:
    $213
    Qty:
    Pack:
    50mg
    Price:
    $359
    Qty:
  6. Description:

    Irreversible tryptophan hydroxylase inhibitor. Depletes 5-HT.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $59
    Qty:
  7. Pack:
    10mg
    Price:
    $163
    Qty:
    Pack:
    50mg
    Price:
    $640
    Qty:
  8. Pack:
    1mg
    Price:
    $35
    Qty:
    Pack:
    5mg
    Price:
    $126
    Qty:
    Pack:
    10mg
    Price:
    $184
    Qty:
    Pack:
    50mg
    Price:
    $660
    Qty:
  9. Chrysomycin A (HB3835)

    Description:

    Topoisomerase II inhibitor

    Purity:

    >98%

    Pack:
    250μg
    Price:
    $184
    Qty:
    Pack:
    1mg
    Price:
    $451
    Qty:
  10. Chrysomycin B (HB3836)

    Description:

    Topoisomerase II inhibitor

    Purity:

    >98%

    Pack:
    250μg
    Price:
    $179
    Qty:
    Pack:
    1mg
    Price:
    $441
    Qty:
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