Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 291-300 of 1076

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  1. DAPT (HB3345)

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    Description:

    γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $168
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    Pack:
    25mg
    Price:
    $418
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    Pack:
    50mg
    Price:
    $703
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    Pack:
    10mM (1mL in DMSO)
    Price:
    $109
    Qty:
  2. Pack:
    1mg
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    Qty:
    Pack:
    5mg
    Price:
    $147
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    Pack:
    10mg
    Price:
    $185
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    Pack:
    50mg
    Price:
    $773
    Qty:
  3. H2DCFDA (HB8322)

    Description:

    Fluorescent dye for ROS and oxidative stress detection. Used to measure redox state of a cell.

    Pack:
    100mg
    Price:
    $70
    Qty:
  4. Pack:
    1mg
    Price:
    $34
    Qty:
    Pack:
    50mg
    Price:
    $835
    Qty:
    Pack:
    5mg
    Price:
    $131
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    Pack:
    10mg
    Price:
    $215
    Qty:
  5. Description:

    Histone methyltransferase inhibitor. Enhances Oct4 expression in chemically-induced pluripotent stem cells.

    Purity:

    >98%

    Pack:
    500μg
    Price:
    $118
    Qty:
    Pack:
    1mg
    Price:
    $173
    Qty:
    Pack:
    5mg
    Price:
    $777
    Qty:
  6. Description:

    Cholesterol biosynthesis inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $441
    Qty:
  7. Description:

    TGF-β signaling inhibitor

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $502
    Qty:
  8. Description:

    Specific DNA polymerase α inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $250
    Qty:
  9. Description:

    Selective α-mannosidase I inhibitor

    Pack:
    5mg
    Price:
    $130
    Qty:
    Pack:
    25mg
    Price:
    $502
    Qty:
  10. Description:

    Manumycin A derivative

    Purity:

    >96%

    Pack:
    5mg
    Price:
    $509
    Qty:
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