Organoids

Organoids are 3D tissue/organ models made up of pluripotent stem cells and other supporting co-cultured cells eg. epithelial cells. Many types of organoids have been developed to date, including brain, pancreas, heart, lung, intestine, liver, optic cup and cancer organoids. They make stable model systems and can be derived from human stem cells or from patient derived iPSCs. Small molecules are increasingly being used to grow and maintain organoids because of their ease of use and controllable quality, enabling consistent, repeatable results. Researchers can save up to 50% on high purity small molecules used to generate organoids – the range from Hello Bio is around half the price of other suppliers.

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Items 11-18 of 18

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  1. IWP 4 (HB3066)

    Description:

    Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $550
    Qty:
  2. KY 02111 (HB3465)

    Description:

    Wnt signaling inhibitor. Promotes differentiation of hESCs and iPSCs into cardiomyocytes.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $168
    Qty:
    Pack:
    50mg
    Price:
    $613
    Qty:
  3. Description:

    Potent, selective ALK2/ALK3 inhibitor which also promotes neural induction of hPSCs. May be used as a component for brain organoid production.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $184
    Qty:
    Pack:
    50mg
    Price:
    $662
    Qty:
  4. PluriSln 1 (HB3573)

    Description:

    SCD1 inhibitor. Selectively eliminates undifferentiated hPSCs from culture.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $450
    Qty:
  5. Rapamycin (HB2779)

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    Description:

    mTOR inhibitor and potent immunosuppressant. Also used in inducible gene editing methods (e.g. CRISPR/Cas9) and promotes hPSC differentiation.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $146
    Free trial
    Qty:
    Pack:
    5mg
    Price:
    $247
    Qty:
  6. SAG (HB3107)

    Description:

    Cell permeable Sonic hedgehog (Shh) agonist and Smo agonist. Enhances neuronal differentiation of iPSC into dopaminergic neurons.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $190
    Qty:
    Pack:
    5mg
    Price:
    $773
    Qty:
  7. Stauprimide (HB3011)

    Description:

    NME2 nuclear translocation inhibitor. Primes ESCs for differentiation.

    Purity:

    >98%

    Pack:
    100μg
    Price:
    $194
    Qty:
  8. Wnt-C59 (HB3155)

    Description:

    Highly potent PORCN inhibitor. Induces iPSC cardiomyocytes differentiation.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $271
    Qty:
    Pack:
    50mg
    Price:
    $1,056
    Qty:
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