ROCK (Rho-kinase)

Broad-spectrum antibiotic. Used in inducible Tet-on/ Tet-off gene expression systems for gene editing.

Highly potent PARP-1 inhibitor

Cell-permeable, non-competitive dynamin inhibitor

Epithelial K_Ca channel activator. Promotes ESC differentiation into cardiomyocytes.

Broad enzyme inhibitor. Inhibits Gq protein signaling.

Synthetic retinoid. Induces neural differentiation of hESCs.

G(2)/M phase cell cycle inhibitor

Ion chelator

Calcium specific chelator

Potent adenosine deaminase and PDE2 inhibitor. Supresses spontaneous hESC differentiation. Also maintains pluripotency of hESCs in the absence of exogenous cytokines.