Cytokine Storm / Immune response signaling
Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.
View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling
Zebularine (HB1378)
Description:DNA methyltransferase inhibitor. Induces cardiomyocyte differentiation in MSCs.
Purity:>99%
Z-Leu-Leu-Glu-AMC (HB4132)
Description:Fluorogenic tri-peptide substrate. Useful for measuring trypsin-like 20S proteasome peptidase activity.
Purity:>95%
Z-Leu-Leu-Leu-AMC (HB4133)
Description:Fluorogenic tri-peptide substrate. Useful for measuring trypsin-like 20S proteasome peptidase activity.
Purity:>95%
Z-Leu-Leu-Leu-B(OH)2 (MG-262) (HB4134)
Description:Highly potent, selective, cell permeable proteasome inhibitor. More potent than MG-132.
Purity:>95%
Z-Leu-Leu-Nva-CHO (HB4136)
Description:Potent, reversible and cell permeable proteasome inhibitor
Purity:>95%
Z-Leu-Leu-Phe-CHO (HB4137)
Description:Reversible and cell permeable proteasome inhibitor
Purity:>95%
Zoledronic acid (HB0674)
Description:Highly potent bisphosphonate, shows variety of biological actions