DREADDs

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

10 Items

Set Descending Direction
  1. Amisulpride (HB1879)

    Description:

    Potent, selective dopamine D2 and D3 receptor antagonist. Atypical antipsychotic.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $124
    Qty:
  2. Description:

    D2 receptor antagonist

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $142
    Qty:
    Pack:
    50mg
    Price:
    $534
    Qty:
  3. Olanzapine (HB1786)

    Description:

    5-HT2A and D2 antagonist. Potent DREADD agonist. Atypical antipsychotic.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $49
    Qty:
    Pack:
    50mg
    Price:
    $195
    Qty:
  4. Paliperidone (HB1798)

    Description:

    5-HT2A and D2 antagonist. Antipsychotic.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $120
    Qty:
    Pack:
    50mg
    Price:
    $438
    Qty:
  5. Description:

    D2 receptor antagonist. Also 5-HT3 and nAChR antagonist.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $78
    Qty:
  6. Description:

    5-HT2 and D2 antagonist. Atypical antipsychotic.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $120
    Qty:
  7. Description:

    Dopamine D2 and D3 receptor agonist

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $131
    Qty:
    Pack:
    50mg
    Price:
    $459
    Qty:
  8. Description:

    5-HT2A and D2 antagonist. Atypical antipsychotic.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $523
    Qty:
  9. Zotepine (HB1778)

    Description:

    5-HT2A and dopamine D2 receptor antagonist. Atypical antipsychotic.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $88
    Qty:
    Pack:
    50mg
    Price:
    $345
    Qty: