Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
Pioglitazone hydrochloride (HB2554)
Description:Selective PPARγ agonist. Enhances mESCs proliferation and survival.
Purity:>99%
Pexidartinib (PLX3397) (HB8991)
Description:Potent CSF-1R inhibitor. Widely used microglia-depletion agent.
Purity:>98%
PLX5622 (HB17582)
Description:Highly selective, potent CSF-1R inhibitor. Widely used microglia-depletion agent.
Purity:>98%
Prochlorperazine dimaleate (HB1907)
Description:D2 receptor antagonist. Also 5-HT3 and nAChR antagonist.
Purity:>99%
Quetiapine hemifumarate (HB1803)
Description:5-HT2 and D2 antagonist. Atypical antipsychotic.
Purity:>99%