Group I (mGlu5, mGlu1)

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Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.

Items 921-930 of 1076

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  1. Stauprimide (HB3011)

    Description:

    NME2 nuclear translocation inhibitor. Primes ESCs for differentiation.

    Purity:

    >98%

    Pack:
    100μg
    Price:
    $188
    Qty:
  2. Pack:
    1mg
    Price:
    $408
    Qty:
  3. Description:

    Glycoside with various biological actions

    Purity:

    >95%

    Pack:
    50mg
    Price:
    $348
    Qty:
  4. Stigmasterol (HB4095)

    Description:

    Phytosterol with anticancer and many other biological actions. Farnesoid X receptor antagonist.

    Purity:

    >95%

    Pack:
    5g
    Price:
    $242
    Qty:
  5. Pack:
    10mg
    Price:
    $235
    Qty:
    Pack:
    50mg
    Price:
    $887
    Qty:
  6. Streptochlorin (HB4096)

    Description:

    TNFα-induced NF-κB activation inhibitor.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $396
    Qty:
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    Description:

    Calcium sensing receptor (CaSR) agonist. Induces MSC osteogenic differentiation.

    Pack:
    1g
    Price:
    $103
    Qty:
  8. SU 5402 (HB3133)

    Description:

    Potent FGFR and VEGFR inhibitor. Attenuates integrin β4-induced neural stem cell differentiation.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $138
    Qty:
  9. Pack:
    100mg
    Price:
    $91
    Qty:
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