DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 201-210 of 747

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  1. DAPT (HB3345)

    1  Review
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    Description:

    γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $168
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    Pack:
    25mg
    Price:
    $418
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    Pack:
    50mg
    Price:
    $703
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    Pack:
    10mM (1mL in DMSO)
    Price:
    $109
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  2. Pack:
    1mg
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    Pack:
    5mg
    Price:
    $147
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    Pack:
    10mg
    Price:
    $185
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    Pack:
    50mg
    Price:
    $773
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  3. Description:

    Histone methyltransferase inhibitor. Enhances Oct4 expression in chemically-induced pluripotent stem cells.

    Purity:

    >98%

    Pack:
    500μg
    Price:
    $118
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    Pack:
    1mg
    Price:
    $173
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    Pack:
    5mg
    Price:
    $777
    Qty:
  4. Description:

    Cholesterol biosynthesis inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $441
    Qty:
  5. Description:

    TGF-β signaling inhibitor

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $502
    Qty:
  6. Description:

    Specific DNA polymerase α inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $250
    Qty:
  7. Description:

    Selective α-mannosidase I inhibitor

    Pack:
    5mg
    Price:
    $130
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    Pack:
    25mg
    Price:
    $502
    Qty:
  8. Description:

    α-glucosidase inhibitor.

    Pack:
    10mg
    Price:
    $187
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    Pack:
    50mg
    Price:
    $726
    Qty:
  9. 2  Reviews
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    Description:

    Potent, selective and metabolically stable hM3Dq and hM4Di muscarinic DREADD actuator.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $58
    Qty:
    Pack:
    10mg
    Price:
    $90
    Qty:
    Pack:
    25mg
    Price:
    $195
    Qty:
    Pack:
    50mg
    Price:
    $316
    Qty:
    Pack:
    100mg
    Price:
    $495
    Qty:
  10. 15  Reviews
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    Description:

    Potent, selective and metabolically stable hM3Dq and hM4Di muscarinic DREADD actuator. Water soluble.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $63
    Qty:
    Pack:
    10mg
    Price:
    $108
    Qty:
    Pack:
    25mg
    Price:
    $216
    Qty:
    Pack:
    50mg
    Price:
    $351
    Qty:
    Pack:
    100mg
    Price:
    $522
    Qty:
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