Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 451-460 of 757

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  1. NBQX (HB0442)

    2  Reviews
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    Description:

    Potent, selective, competitive AMPA receptor antagonist

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $166
    Qty:
    Pack:
    50mg
    Price:
    $697
    Qty:
  2. 30  Reviews
    Top Reviews:
    99% of 100
    Add Your Review
    Description:

    Potent, selective, competitive AMPA receptor antagonist. Disodium salt.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $89
    Qty:
    Pack:
    10mg
    Price:
    $185
    Free trial
    Qty:
    Pack:
    50mg
    Price:
    $783
    Qty:
    Pack:
    50mM (add 1ml water)
    Price:
    $441
    Qty:
    Pack:
    100mM (add 1ml water)
    Price:
    $768
    Qty:
  3. Nebularine (HB3992)

    Description:

    Naturally occuring nucleoside. DNA, RNA and protein synthesis inhibitor.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $183
    Qty:
  4. Necrostatin-5 (HB3994)

    Description:

    Necroptosis inhibitor. Indirect RIP1 kinase inhibitor.

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $222
    Qty:
  5. Necrostatin-7 (HB3995)

    Description:

    Necroptosis inhibitor. Shows no action at RIP1 kinase.

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $389
    Qty:
  6. Neoxaline (HB3996)

    Description:

    G2/M phase cell cycle inhibitor

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $174
    Qty:
    Pack:
    5mg
    Price:
    $699
    Qty:
  7. Neuropathiazol (HB3105)

    Description:

    Selective neuronal differentiation inducer in hippocampal neural progenitors

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $187
    Qty:
    Pack:
    50mg
    Price:
    $733
    Qty:
  8. NF 449 (HB1961)

    Description:

    Potent, selective, competitive P2X receptor antagonist

    Purity:

    >95%

    Pack:
    10mg
    Price:
    $210
    Qty:
    Pack:
    50mg
    Price:
    $838
    Qty:
  9. Pack:
    10mg
    Price:
    $51
    Qty:
    Pack:
    50mg
    Price:
    $200
    Qty:
  10. Description:

    Inactive control compound for hedgehog signaling inhibitor 22-NHC

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $229
    Qty:
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