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Biological Data
| Biological description | Potent, selective and competitive P2X receptor antagonist. Selective for P2X1 receptors (IC50 values are 0.3 and 0.7 nM, 0.3, 1.8, 47 and >300 µM for P2X1, P2X1 + 5, P2X2 + 3, P2X3, P2X2 and P2X4 receptors respectively). Also inhibits FGFR3. Shows potential anti-cancer and anti-thrombotic actions. |
Solubility & Handling
| Storage instructions | Room temperature |
| Solubility overview | Soluble in water |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 4,4',4'',4'''-[Carbonylbis(imino-5,1,3-be nzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzen edisulfonic acid, octasodium salt |
| Molecular Formula | C41H24N6Na8O29S8 |
| PubChem identifier | 91895233 |
| SMILES | [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)C1=CC=C(NC(=O)C2=CC(=CC(NC(=O)NC3=CC(=CC(=C3)C(=O)NC3=CC=C(C=C3S([O-])(=O)=O)S([O-])(=O)=O)C(=O)NC3=CC=C(C=C3S([O-])(=O)=O)S([O-])(=O)=O)=C2)C(=O)NC2=CC=C(C=C2S([O-])(=O)=O)S([O-])(=O)=O)C(=C1)S([O-])(=O)=O |
| InChiKey | PHCBPKWKKHYRSA-UHFFFAOYSA-F |
Potent, selective, competitive P2X receptor antagonist
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