NG,NG-Dimethylarginine Dihydrochloride

(HB0449)
Technical documents: Datasheet

Product overview

Name NG,NG-Dimethylarginine Dihydrochloride
Purity >98%
Description Competitive NOS inhibitor
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Biological Data

Biological description Competitive NOS inhibitor. Produced endogenously. Used as a biomarker.

Solubility & Handling

Solubility overview Soluble in water (100 mM)
Storage instructions Room temperature (desiccate)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name (2S)-2-amino-5-[[amino(dimethylamino)methylidene]amino]pentanoic acid dihydrochloride
Molecular Weight 275.18
Chemical structure NG,NG-Dimethylarginine Dihydrochloride  [220805-22-1] Chemical Structure
Molecular Formula C8H18N4O2.2HCl
CAS Number 220805-22-1
PubChem identifier 16219246
SMILES CN(C)C(=NCCC[C@@H](C(=O)O)N)N.Cl.Cl
InChi InChI=1S/C8H18N4O2.2ClH/c1-12(2)8(10)11-5-3-4-6(9)7(13)14;;/h6H,3-5,9H2,1-2H3,(H2,10,11)(H,13,14);2*1H/t6-;;/m0../s1
InChiKey SYLNVYJOPZWPJI-ILKKLZGPSA-N
MDL number MFCD00270857

References for NG,NG-Dimethylarginine Dihydrochloride

References are publications that support the biological activity of the product
  • Dimethylarginines ADMA and SDMA: the real water-soluble small toxins?

    Schepers E et al (2014) Semin Nephrol 34(2) : 97-105.
  • Monitorization of asymmetric dimethylarginine (ADMA) levels in an experimental ischemia-reperfusion flap model: a preliminary report.

    Karaaslan O et al (2013) J Reconstr Microsurg 29(6) : 417-20.

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