Hedgehog signaling

Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.

BET bromodomain inhibitor, also promotes differentiation of hiPSCs into megakaryocytes

Non-selective, competitive cAMP and cGMP PDE inhibitor. Facilitates neural progenitor cell differentiation.

Neurogenic agent. Induces SVZ progenitor neuronal differentiation and cardiomyogenic differentiation.

Selective TGF-β signaling inhibitor. Induces cardiomyocyte differentiation in ESCs.

Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.

Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.

Downstream Hedgehog signaling pathway inhibitor. Alcohol dehydrogenase 7 inhibitor.

Potently induces chondrogenesis in MSCs

Potent CDK inhibitor. Also GSK-3 inhibitor. Generates iPSCs.