PI3K/Akt/mTOR

Non-selective, competitive cAMP and cGMP PDE inhibitor. Facilitates neural progenitor cell differentiation.

Tyrosine kinase inhibitor that targets BCR‑ABL, c‑KIT, and PDGFR kinases

Cyclooxygenase inhibitor

Neurogenic agent. Induces SVZ progenitor neuronal differentiation and cardiomyogenic differentiation.

Selective TGF-β signaling inhibitor. Induces cardiomyocyte differentiation in ESCs.

α7 nicotinic acetylcholine receptor positive allosteric modulator. Activates GluCI/GlyCI chemogenetic channels. Shows antiviral activity.

Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.

Potently induces chondrogenesis in MSCs

Wnt signaling inhibitor. Promotes differentiation of hESCs and iPSCs into cardiomyocytes.

Potent, selective ALK2/ALK3 inhibitor which also promotes neural induction of hPSCs. May be used as a component for brain organoid production.